Module 4: Lung Defences Against The Environment - Neutrophils and Local Immunoglobulins |
The lung is capable of a range of immunological responses, usually initiated by alveolar macrophages.
Alveolar macrophages may recruit neutrophils into the lung and alveoli, for example, in the case of pneumonia.
They may stimulate B cells to produce specific IgM or IgG immunoglobins, or via T H2 cells result in recruitment of eosinophils and IgE production. IgA production is a normal function of B cells in subepithelial lymphoid aggregates in the airways.
Postgraduate Diploma in Occupational Health (DOH) - Modules 3 – 5: Occupational Medicine & Toxicology by Prof Rodney Ehrlich & Prof Mohamed Jeebhay is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.
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