Block 1: Epidemiology |
EPI4-5 THE ODDS RATIO |
SESSION OBJECTIVE |
At the end of this session you should have an understanding of the relationship between the OR and the IRR |
The relationship between the Odds Ratio, OR, and the Incidence Rate Ratio, IRR, is a little more difficult to grasp.
D+ | D- | ||
E+ | a | c | M1 |
E- | b | d | M0 |
N1 | N0 | T |
From the table above it can be seen that
IRR = I1/I0 = (a/PYR1)/(b/PYR0)
where:
a is the number of disease cases in the exposed group
b is the number of disease cases in the non-exposed group
PYR1 is the person-years in the exposed group
PYR0 is the person-years in the unexposed group
If the controls are representative of the exposure distribution in the population that generates the cases, then c and d should be good estimators of PYR1 and PYR0.
And so, IRR ~ ad/bc
Interactive ExamplesThe Examples listed below have been included in order to illustrate the concepts discussed in this Section. |
Question 1 | Question 3 | Question 5 |
Question 2 | Question 4 | Question 6 |